Which of the following statements about normal cells is true?

Normal cells maintain a small nuclear-cytoplasmic ratio, which is a characteristic distinguishing them from cancer cells. In healthy cells, the nucleus occupies a smaller portion of the cell, as the majority of the cell's volume is filled with cytoplasm. This small ratio is indicative of normal cellular function and growth regulation. Conversely, cancer cells typically exhibit an enlarged nucleus relative to their cytoplasmic volume, reflecting their abnormal growth and behavior. This is an essential aspect of cell biology that helps in identifying whether a cell is functioning normally or has become neoplastic.

The other statements reflect characteristics associated with abnormal or cancerous cells rather than normal cells, highlighting the importance of differentiating normal cellular characteristics from those of malignant cells in oncology nursing practice.